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LOT #VY20261005

5 Oct 2026 · Janoshik

≥ 99 %
Research Use OnlyMetabolic research

MOTS-c

16-amino-acid mitochondrial peptide studied in metabolic research.

43,90 €
In stock
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99.1% purity · Lyophilized powder
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MOTS-c

10 mg · 43,90 €

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Description

MOTS-c (Mitochondrial ORF of the 12S rRNA type-c) is a 16-amino-acid peptide of mitochondrial origin, studied as a research tool for metabolic homeostasis and the AMPK pathway in laboratory models. Supplied lyophilised with an independent certificate of analysis. Intended exclusively for scientific research in the laboratory — not intended for human consumption.

Research peptides — Research Use Only

  • Not for human consumption
  • Not for the diagnosis, treatment or prevention of any disease

Reconstitution calculator

Pre-filled for this peptide. Adjust the water added and target dose to get the volume to draw.

Calculation result

Draw the syringe to

10

units

Volume

0.1

mL

Concentration

5

mg/mL

Draws / vial

20

Level on a graduated syringe 1 mL (100 U)

0102030405060708090100Draw the syringe to 10 U
Draw frequency :

This vial lasts 10 weeks

Syringe size

Step 1

Target dose

the amount of peptide targeted

0.5 mg

0.5 mg = 500 mcg (µg)

Step 2

Vial dosage

total peptide mass, in mg

10 mg

Step 3

Bacteriostatic water

reconstitution volume, in mL

2 mL

MOTS-c — Research protocol

Mitochondrial-derived peptide

Dose (study protocol)
5–10 mg per administration
Frequency
3–5×/week (s.c.)
Duration (published studies)
4–12 weeks (murine models)

Source : Lee et al., Cell Metabolism 2015

No published human study. Murine doses: 2.5 mg/kg twice daily i.p. (Lee 2015).

This data comes from published studies compiled for informational purposes for laboratory professionals. No dose is recommended. Not intended for human consumption or animal use.

Read the full analysis MOTS-c

Get your complete protocol

Personalised numeric summary + a printable step-by-step reconstitution procedure. We email it to you as a PDF.

How It Works

  1. 1. Concentration

    Divide vial amount (mcg) by water volume (mL) to get concentration (mcg/mL).

  2. 2. Volume needed

    Divide desired dose by concentration to get injection volume in mL.

  3. 3. Syringe units

    Multiply mL × 100 to get U-100 syringe units (IU).

Example

  • 5 mg vial + 2 mL water = 2.5 mg/mL
  • Want 250 mcg (0.25 mg)?
  • 0.25 ÷ 2.5 = 0.1 mL
  • 0.1 mL = 10 units on a U-100 syringe

Research Use Only

This calculator is for research purposes only. Not medical advice.

Common Conversions

1 mg
1,000 mcg
500 mcg
0.5 mg
250 mcg
0.25 mg
100 mcg
0.1 mg

Syringe Units

0.3 mL syringe
30 units
0.5 mL syringe
50 units
1.0 mL syringe
100 units

Volumetric conversion tool for laboratory handling. Not any human or animal administration advice. Research use only.

Highlights

Why this research peptide

Mitochondrial peptide

Encoded by the mitochondrial genome, MOTS-c belongs to the family of mitochondrial-derived peptides (MDP).

AMPK pathway studied

Documented in vitro for activation of AMP-activated protein kinase and regulation of energy metabolism.

Metabolic homeostasis

Studied in laboratory models for its role in glucose metabolism regulation.

Verified purity

HPLC + mass spectrometry analysis by an independent laboratory, certificate included with each batch.

Long-term storage

Lyophilised form stable up to 24 months at -20°C for prolonged laboratory storage.

Discreet logistics

Shipped from the EU, delivery within 1–2 days, tracking included and neutral packaging.

What is MOTS-c?

MOTS-c is a 16-amino-acid peptide encoded by the mitochondrial genome, belonging to the family of mitochondrial-derived peptides. It is used as a reagent to study metabolic homeostasis in laboratory models. Supplied lyophilised with an independent certificate of analysis, intended exclusively for scientific research — not intended for human consumption.

Storage & handling

Temperature
-20°C (lyophilised) / 2-8°C (in solution)
Conditions
Away from light and moisture
Shelf life
24 months (lyophilised, sealed)

Product intended exclusively for scientific research in the laboratory. Keep in its original packaging until use.

Published research data

The works below document the pharmacology of MOTS-c. They are cited as scientific context and do not constitute a product claim.

  1. 1

    Cell Metabolism (2015) — PMID 25738459

    Foundational work describing MOTS-c as a regulator of metabolic homeostasis via the AMPK pathway in preclinical models.

Mechanisms studied in research

The literature describes several pathways studied in vitro and in preclinical models. The items below summarise these mechanisms for information only, with no intended human use.

1

AMPK pathway

Studied for activation of AMP-activated protein kinase, a central regulator of energy metabolism.

2

Glucose metabolism

Documented in preclinical models for its influence on glucose homeostasis and insulin sensitivity.

3

Nuclear translocation

Described as migrating to the nucleus under metabolic stress, in association with antioxidant response elements.

Questions about this product

Who is this product intended for?
This product is a reagent intended exclusively for research professionals and institutions, for in vitro use in the laboratory. It is not intended for the general public.
Is the product intended for human consumption?
No. All our products are research peptides (Research Use Only), not intended for human consumption, nor for the diagnosis, treatment or prevention of any disease.
How are batches verified?
Each batch is analysed by an independent laboratory (HPLC for purity, mass spectrometry for identity). The certificate of analysis (CoA) is included with every order.
What are the delivery times?
Shipped from the EU in a discreet parcel with tracking. Fast delivery within 1–2 days (business days). Intra-EU shipping: no customs, no import delays. Physically controlled stock, original sealed vials. EU delivery with no customs. Neutral and discreet packaging.
What payment methods are accepted?
Visa, Mastercard, Apple Pay, Google Pay and crypto. Secure 3D-Secure payment.
How should a lyophilised peptide be stored?
The sealed lyophilisate is stored at -20°C, away from light and moisture. Refer to the CoA and storage sheet for batch-specific details.
Is the certificate of analysis provided?
Yes, an independent certificate of analysis is included with every order to guarantee purity and identity.
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