Semax
ACTH(4-10) analogue · Met-Glu-His-Phe-Pro-Gly-Pro
Le Semax est un heptapeptide de synthèse (Met-Glu-His-Phe-Pro-Gly-Pro) analogue du fragment ACTH(4-10). Il est étudié in vitro et en modèle préclinique pour la modulation du système neurotrophique BDNF/TrkB et des mécanismes neuroprotecteurs. Réactif destiné exclusivement à la recherche en laboratoire — non destiné à la consommation humaine.
En bref
- Classe
- Heptapeptide (7 aa)
- Origine
- Analogue de l'ACTH(4-10)
- Forme
- Lyophilisée (poudre)
- Statut
- Research Use Only
Axes de recherche documentés
Bibliothèque d'études
Tous les résultats sur PubMedTherapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
Rahman OF, et al. · Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
Semax peptide targets the μ opioid receptor gene Oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female mice.
Liu R, et al. · British journal of pharmacology · 2025
Functional Connectomic Approach to Studying Selank and Semax Effects.
Panikratova YR, et al. · Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2020
The Effect of Peptide Semax, an ACTH(4-10) Analogue, on Intracellular Calcium Dynamics in Rat Brain Neurons.
Kolbaev SN, et al. · Bulletin of experimental biology and medicine · 2025
The Potential of the Peptide Drug Semax and Its Derivative for Correcting Pathological Impairments in the Animal Model of Alzheimer's Disease.
Radchenko AI, et al. · Acta naturae · 2025
Specific binding of semax in different regions of the rat brain.
V'yunova TV, et al. · Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2006
The action of the peptide drug Semax on the currents of AMPA receptors of rat cerebellar Purkinje cells.
Grigoriev VV, et al. · Doklady. Biochemistry and biophysics · 2015
Peptides semax and selank affect the behavior of rats with 6-OHDA induced PD-like parkinsonism.
Slominsky PA, et al. · Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2017
Semax, a Copper Chelator Peptide, Decreases the Cu(II)-Catalyzed ROS Production and Cytotoxicity of aβ by Metal Ion Stripping and Redox Silencing.
Tomasello MF, et al. · Bioinorganic chemistry and applications · 2025
[Study of the efficacy of semax in global cerebral ischemia in vivo].
Iakovleva EV, et al. · Biulleten' eksperimental'noi biologii i meditsiny · 1999
Neuroprotective and antiamnesic effects of Semax during experimental ischemic infarction of the cerebral cortex.
Romanova GA, et al. · Bulletin of experimental biology and medicine · 2006
[Use of semax at a follow-up of patients with posthypoxic encephalopathy].
Alekseeva GV, et al. · Anesteziologiia i reanimatologiia · 1999
Résultats récupérés en direct depuis PubMed (NCBI). Littérature de recherche uniquement — aucun conseil médical.
Peptides de recherche — Research Use Only
- Non destinés à la consommation humaine
- Non destinés au diagnostic, au traitement ou à la prévention d'une maladie